Spinal Fluid Lactate Dehydrogenase Level Differentiates between Structural and Metabolic Etiologies of Altered Mental Status in Children

KHOSROSHAHI, Nahid and ALIZADEH, Parastoo and KHOSRAVI, Mehdi and SALAMATI, Peyman and KAMRANI*, Kamyar (2015) Spinal Fluid Lactate Dehydrogenase Level Differentiates between Structural and Metabolic Etiologies of Altered Mental Status in Children. Iranian Journal of Child Neurology, 9 (1). pp. 31-36.

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Abstract

Objective
Altered mental status is a common cause of intensive care unit admission in
children. Differentiating structural causes of altered mental status from metabolic etiologies is of utmost importance in diagnostic approach and management of the patients. Among many biomarkers proposed to help stratifying patients with altered mental status, spinal fluid lactate dehydrogenase appears to be the most promising biomarker to predict cellular necrosis.

Materials & Methods
In this cross sectional study we measured spinal fluid level of lactate
dehydrogenase in children 2 months to 12 years of age admitted to a single center intensive care unit over one year. Spinal fluid level of lactate dehydrogenase in 40 pediatric cases of febrile seizure was also determined as the control group.

Item Type: Article
Subjects: Apsci Archives > Medical Science
Depositing User: Unnamed user with email support@apsciarchives.com
Date Deposited: 08 Mar 2023 09:37
Last Modified: 02 Mar 2024 04:37
URI: http://eprints.go2submission.com/id/eprint/479

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