EFFECTS OF LOCAL VIBRATION THERAPY ON LOWER LIMB’S SENSORIMOTOR CONTROL IN WORKERS SUFFERING FROM DIABETIC FOOT – STATE OF ARTS AND STUDY ON A NEW PREVENTION AND THERAPEUTIC SYSTEM

Diabetes mellitus is a pathology constantly expanding worldwide and, along with its complications, is a major challenge for medicine. To understand the dimensions of this disease, we may refer to the data from the World Health Organization [1] [WHO] according to whom there are about 366 million people suffering from diabetes or pre diabetes worldwide, a number which is expected to grow inexorably as a result of population growth and aging, besides the high prevalence of obesity and overweight leading to changes in lifestyle. In Countries with a particularly high rate of growth [BRIC] Brazil, Russia, India, China the disease is forecasted to expand explosively. Type 2 diabetes is increasing in all westernized countries, although significant differences are noted among different ethnic groups. The genetic and ethnic basis which contributes to the different expression and the development of diabetes, namely its complications, are in the process of being understood. Recent studies have shown that people of Asian origin [India, Pakistan, and Bangladesh] tend, more than Caucasians, to have a higher incidence of diabetes, especially of type 2, characterized by a high resistance to the action of insulin. However the incidence of obesity, an important risk factor in the development of type 2 diabetes, is significantly lower in Asian Indians compared to Caucasians. Changes in lifestyle, more western and sedentary, are not completely useful to clarify this difference. The resistance to the action of insulin, on one hand, helps to understand the increased incidence and, on the other hand, it leaves open the debate on its causes. Moreover, as in Caucasians, the expression of serious complications such as microangiopathy, requires the presence of the genetic-biochemical alterations, so some changes in the expression of diabetes in the Asian regions may be related to factors scrambling gene, linked to colonialism. In fact, studies indicate a significant difference in the expression of diabetes and its complications [see fat distribution and microangiopathy] between Asian cities [Madras-Chennai] with long colonial presence, especially English, and campaigns. Diabetes is often undiagnosed or highlighted in the course of clinical trials or for the appearance of its dangerous complications. (See Table 1). In particular, in this work, we stress the problems of the diabetic foot. In its various expressions such as neuropathic, vascular and mixed, and propose the preliminary results of a new therapeutic approach of this complication, so serious as well as so much misunderstood. In particular, it wanted to see if, in the diabetic foot conditions with alterations in the sensitivity, but not yet microangiopathic, mechanical stimulation at low frequency, and amplitude [maximum 50 hz and a millimeter], [2] could induce, through the increase of the production of nitric oxide, [3] a vasodilation with an improved surface perfusion, thus inhibiting the tendency to neoangiogenesis of a pathological vascular tissue, highly sensitive to age-rage reactions, with the consequent inflammatory phenomena and the production of free radicals and superoxides, real cause the serious pathological evolution of microangiopathic diabetic foot.