Effect of Acute Toxicity of Lead Nitrate on Serum Biochemical and Enzymological Parameters of Indian Major Carp, Labeo rohita

To determine the LC 50 value of lead nitrate, Labeo rohita were exposed to different concentrations of the heavy metal through static assay method. LC50 value was calculated by employing Probit analysis and its acute toxicity was found to be 851mg/L. The acute toxic effect of lead nitrate on serum biochemical parameters of Labeo rohita were studied through 96-hour acute toxicity assay. Significant alterations were noticed in serum biochemical parameters viz. Total protein, Albumin, Globulin, and enzymes like Serum glutamate oxalate transaminase (SGOT), Serum glutamate pyruvate transaminase (SGPT) and Alkaline phosphatase (ALP). There was an increase in the mean values of total protein, albumin, globulin, SGOT, SGPT and ALP in lead nitrate exposed fishes when compared to the control fishes, but fluctuations were noticed in the ALP mean values.