A Systematic Review on the Comparison of Tissue Substitutes with Subepithelial Connective Tissue Graft in Root Coverage

This chapter aims to evaluate the efficacy of soft tissue substitutes namely Acellular dermal matrix (ADM), Collagen matrix (CM) and Titanium-prepared platelet-rich fibrin (T-PRF) in comparison to subepithelial connective tissue graft (SECTG) by tunnel or modified coronally advanced tunnel technique (MCAT) in root coverage.

A literature review on the effectiveness of soft tissue substitutes in comparison to SECTG by tunnel technique or modified coronally advanced tunnel technique for root coverage procedures was conducted using MEDLINE, PubMed, Cochrane libraries, EMBASE, and hand searched journals from January 1999 to August 2020.For the qualitative synthesis, seven studies were included. SECTG, ADM, and T-PRF were found to be more effective for complete/partial root coverage. According to Miller's classification, this was the primary outcome. When secondary outcomes were considered, SECTG performed better. For root coverage, the clinical efficacy of SECTG appeared to be higher in tunnel or modified coronally advanced tunnel techniques. As a result, SECTG may be a better option than other substitutes.