Larvicidal Activities of Hyptis suaveolens and Ocimum sanctum against Anopheles gambiae

Aim: To determine the larvicidal activities of Hyptis suaveolens and Ocimum sanctum against Anopheles gambiae.

Study Design: A 24 h LC50 concentration-mortality static non-renewal bioassay was carried out.

Place and Duration of Study: The study was carried out at Rohi Biotechnologies Ltd’s Toxicity Laboratory, Port-Harcourt, Rivers State Nigeria, between January and March 2015.

Methodology: The solvent extracts were assessed against the mosquito larva at varying concentrations in a 2-phased rapid and final screening test.

Results: Results show that the methanol extract of H. suaveolens induced the highest mortality with LC50 values of 73.25 ppm, while the chloroform and hexane extracts induced mortalities with LC50 values of 76.25 and 97.25 ppm respectively. On the other hand, the O. sanctum extracts induced mortalities of 125.00, 150.00 and 194.08 ppm for methanol, chloroform and hexane extracts respectively.

Conclusion: Based on our findings, we recommend solvent extracts of H. suaveolens and O. sanctum as prospective larvicides in the integrated management of malaria.